“…Not surprisingly, the predominant neurocircuitry model of PTSD postulates deficient inhibitory control of the ventromedial prefrontal cortex (vmPFC) over the fear response (Pitman et al, 2012; Rauch, Shin, & Phelps, 2006), characterized with hypo-activity of the vmPFC (Hayes et al, 2012; Patel et al, 2012), as well as diminished functional (Sripada et al, 2012) and structural (Koch et al, 2017) connectivity between the amygdala, vmPFC and hippocampus. Of note, the vmPFC and hippocampus are important nodes of the default mode network (DMN), which is an intrinsic connectivity network engaged during rest and involved in internally focused thought (Greicius, Krasnow, Reiss, & Menon, 2003).…”