“…It has been previously presented that anterior cingulate cortex is involved in attentional and emotional processes, detection of relevant stimuli and it is important part of cortico-subcortical loop involved in fear conditioning (Eser et al 2009, Javanmard et al 1999, Jensen et al 2003, Ketter et al 1996, Klumpp et al 2014, Phelps et al 2004, Schunck et al 2006, Servan-Schreiber et al 1998, Straube et al 2010. It was shown that anterior cingulate cortex is involved in pathophysiology of anxiety disorder, usually manifested by elevated activity (Bremner et al 2005, Brühl et al 2014, Dilger and Straube 2003, Klumpp et al 2014, Kopřivova et al 2011, Lorberbaum et al 2004, McClure et al 2007, Monk et al 2008, Nitschke et al 2009, Saxena and Rauch 2000, Straube et al 2004a, 2004b, Wright et al 2003, although it was also shown that after exposition of incongruent stimulus subjects with anxiety disorders had smaller activity in anterior cingulate cortex (Etkin et al 2010). The increase of activity in anterior cingulate cortex and anterior part of insula in subjects with anxiety disorders often correlates with elevated activity in amygdala (Brühl et al 2014, Shin andLiberzon 2010).…”